Within the easiest terminology, OSA is due to narrowing otherwise failure of your airway while the due to anatomical and physiological abnormalities in the pharyngeal structures. Apnea episodes cause hypoxemia (not enough clean air in the bloodstream) and you may hypercapnia (large intensity of bloodstream carbon dioxide). The newest episodes also increase the fresh output of one’s sympathetic neurological system (Narkiewicz and you may Somers, 2003), the end result at which would be to fix pharyngeal muscle tone and you can reopen the fresh airway. An entire pathophysiology from OSA remains a bit elusive, even if studies are assembling the brand new dating ranging from OSA and a list of the brand new in the past discussed enough time-label fitness effects. The new etiology of main bed apnea, even when in addition to not well-understood, try hypothesized to originate from instability away from respiratory handle facilities (Light, 2005).

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